Dr. Mikhail Blagosklonny: Researching on Cancer Treatments and Balancing Treatment Cost

Recap: Dr. Mikhail Blagosklonny on Rapamycin’s Incredible Healing Properties

Cancer is killing more people today than any other time in human history. At an early stage, cancer can be treatable, but when it is at an advanced stage, it ‘s hard to manage it. However, researchers are not giving up, and more studies are being conducted to understand this killer disease. One of such researchers is Mikhail Blagosklonny. Mikhail is a professor of oncology and works with the Rosewell Park Cancer Institute in Buffalo, New York. He is also an Editor-in-Chief of the Oncotarget. He is involved in cancer research and therapies and believes that Rapamycin is the best drug for cancer patients and can help increase their lifespan.Rapamycin has traditionally been used to prevent organ transplant rejection and to treat a rare lung disease.

However, the drug is also considered a good cancer drug. This medication has been termed by many as a miracle drug because it can treat many conditions. The drug has also been known to treat patients suffering from a condition brought about by kidney failure and anemia. The condition is known as a hemolytic-uremic syndrome.Rapamycin also helps in the treatment of Tuberous Sclerosis Complex which is a disorder that results in brain tumors, heart tumors, and tumors in other body organs. Rapamycin can also increase longevity. However, this is still not a certain fact. Research is still ongoing, and Dr. Mikhail is spearheading this research. The treatment of Alzheimer’s disease, Systematic Lupus Erythematosus, and Muscular Dystrophy is another plus for the drug.

Recap: Mikhail Blagosklonny’s Plans for Oncology

Dr. Mikhail Blagosklonny has a passion for ensuring that people of all economic standing get the best cancer care regardless of whether they can afford it or not. His work does not only revolve around cancer but aging as well. He continues to research on the causes of cancer and the reason it is affecting people of a particular age group.As a researcher, he is respected and is broadly influential among his peers. As part of his research, Dr. Mikhail is trying to figure out how to treat cancer without the patients incurring too much cost as they do today. He knows that cancer is causing havoc in our society and he hopes he can come up with a way to destroy cancer cells in a person’s body without tampering with the normal human cells.Though his research is yet to bear fruits, he is making remarkable progress. He knows that his work will help many and he hopes that one day, someone else will take over from where he will have left off his research. The society cannot ignore the fact that cancer is becoming one of the deadliest diseases in our society today. Unfortunately, the treatment for cancer can only be afforded by the well-off. So what happens to those people who can’t afford the treatment? Dr. Mikhail Blagosklonny is hoping to solve that issue and also to create a cancer-free society.

The Advantages of Beneful Wet Dog Food

For years, Beneful wet dog food has been a popular selection, especially among the small toy breeds. Dogs typically prefer Beneful wet food because of its high moisture content, and it also increases hydration.

Owners will typically purchase wet dog food as canines age. It’s perffect for older dogs who are beginning to lose the sense of smell or have a capricious appetite, and need more incentive to eat. The wet feed is also great source of hydration for dogs who do not drink as much water as they should.

With BenefulWalmart, you have a wide variety of products to choose from, like Beneful wet dog food incredibites or the chopped blends. The varieties are offered in beef, chicken or turkey and include vegetables like carrots, peas, and brown rice. Beneful selections are also easy on the pockets. Walmart offers individual selections of incredibites for less than $1.75 each.

Just remember, a good diet is essential for your dog, and Beneful provides quality meals through all the stages of your canine’s life.

Different Ways Scientists are Appreciating Precision Medicine in Journals Published on Oncotarget

Cancer treatment has changed over the last few decades as scientists are now using precision medicine. By using precision medicine, researchers have a better understanding of tumor biology of each individual patient. With the understanding, the researchers are accurately defining the prognosis of each given cancer and hence designing targeted treatment for specific molecular alterations. In several journals published on Oncotarget, it is clear that scientists are concentrating on molecular features and characteristics specific to cancer tissues to come up with medication that has minimal effect on healthy tissues.

Breast Cancer Treatment

One of the major milestones achieved by precision medicine is the understanding the biology of breast cancer. This type of cancer is complex and is characterized by diverse tumors and multiple types of the disease. Using PM, scientists have managed to discover the two major predictive makers of breast cancer and these include estrogen receptor (ER) and human epidermal growth factor (HER2). This understanding has helped scientists come up with targeted therapy depending on the type of maker present  and more information click here.

Determining Drug Effectiveness in Humans

Through the years, precision medicine has made significant milestones in helping scientists find a cure for different types of cancer. Oncotarget, on the other hand, has concentrated on publishing research relevant to oncology and what Oncotarge knows. One of the recent publications was a research done by Norris Cotton Cancer Center led by Alan Eastman. The research focused on drugs tried on mice worked with the same mechanism in humans. The researchers used cancer drug gemcitabine for both animal and human models. In their research, the team was able to determine the mechanism in which the drug works when treating cancer in humans and Oncotarget lacrosse camp.

About Oncotarget

Oncotarget is a peer-reviewed open access weekly medical journal covering oncology. The journal was established in 2010 and over the years, the journal, which is published by Impact Journals, has published several articles that help cancer treatment research. Mikhail Blagosklonny and Andrei V. Gudkov are the chief editors. Scientists are free to submit their research to the journal, but you have to ensure that your article meets all the publication ethics and Oncotarget on Facebook.

More Visit: https://oncotarget.msubmit.net/cgi-bin/main.plex

Highland Capital Management Brings the Wisdom of Safe Investment

Highland Capital Management is an investment and financial advisory company operating with a valuation of $ 15.4 billion in assets. It is among the reliable entities in Texas that have brought economic stability or better still financial sanity. Its highly successful affiliated company Highland Alternative investors under Michael Gregory, the Chief Investment Officer and James Dondero – the co-founder.

Gregory is the financial brain for the group who manages the small capitalization stock fund that has almost tripled under his tenure. He has an undisputed mastery of profitable investment venture and accords his felt impact to credit competency of Highland Capital Management. These investments have yielded great returns about half of all the annual revenues according to the comprehensive financial statement of 2016.

Highland Alternative Investors manages a portfolio of products along five major lines: healthcare, real estate, energy, financials and consumer discretionary. Healthcare stocks are the most promising. For companies such as Colleguim and Pacira Pharmaceuticals growth in sales and market share is notable. Real estate investment trusts (REITs) is another managed dimension with skyrocketing gains. Western Gas Equity Partners and Tesoro Logistics LP has been earning a dividend of 4.08% and 6.36% respectively. Financial management guarantees efficiency while assets are managed to be high-performing.

About Highland Capital Management
It was established in 1993 through a partnership pact of James Dondero and Mark Okada and placed the main offices in Dallas, Texas. It has subsidiary operations in Sao Paulo, Singapore, Seoul and the City of New York. Highland Capital Management core operations are in hedge funds, collateralized loans, alternative investment, pension plans, private equity ( in distressed or unique stocks) and emerging market trends. Its clientele includes individuals, corporate, financial institutions and government.

Highland Capital Management has found expansion opportunities through partnering with other entities including countries. Their healthcare private, focused equity fund lead to working with South Korea’s National Pension Service and the Stonebridge Capital. It also has found roots in Asia, China, U.K and North America. Other than wealth creation, Highland Capital Management has been in CSR since 2005 and spent over $ 10 million to support community work and charity events.

Clay Siegall: Passion, Desire & Excellence

Did you know that some of the most extraordinary people in the world aren’t household names? Life is strange in a sense. It seems like the people who don’t do anything for society, receives the credit and vice versa. Have you ever heard of a guy named Clay Siegall? Well, you probably haven’t and this person personifies this notion perfectly. Clay Siegall is one of the most revered individuals in the cancer fighting world. He has a resume of success that spans into decades of the past. Siegall is the current CEO of Seattle Genetics. This biotech company is the leading cancer research company in the world as it specializes in developing and commercializing antibody-based therapies.

Since its inception back in 1998, Seattle Genetics has grown dramatically in physical size as well as employee personnel. There are well over 1,000 people working here, and every person works their job to the very best of their abilities. Siegall is the commander of this ship, which has taken the company into the stratosphere. Its flagship drug ADCETRIS is one of the most successful cancer fighting drugs of all-time. As of today, ADCETRIS has raked in $350 million in earnings. Thanks to Siegall’s ability to negotiate, the drugs are now being used in 65 different countries around the world. This is what obtaining a strategic license can do for a company and Seattle Genetics demonstrates this brilliantly.

Blogging is something that Siegall loves to do in his free time. The guy is constantly updating the community with breaking news in cancer research, and he is known to speak on a wide array of topics. It’s easy to see why this guy is a leader, and his track record is proof of his success. His dedication to each and every patient is extraordinary, which shows you how much he has invested in what he does for a living. Clay Siegall is the real deal when it comes to getting things done thanks to his passion, desire and excellence.

Lori Senecal – Building More Than a Team

Lori Senecal is a renowned advertisement executive and the current Chief Executive of CP+B a global advertising agency. She is in charge of the company’s international offices and manages growth, productivity, and general operations. As CEO, she has transformed the company’s culture into that of collaboration, consistency, result consciousness and invention and innovation. The business has delivered tremendous growth focusing on localized services and products for the international markets.

Since 2015, Lori Senecal has enabled revenue growth in the company by 21%. She uses her creativity to create campaigns that generate value for the client and company. One such campaign is the Letgo campaign, where Lori led her team to develop Commercializer, a tool that enabled the classified-ad app users to create TV-style segments for used items. After the campaign, the app generated over 45 million downloads. She used an almost similar approach for the Kraft Mac & Cheese campaign and NBA 2K.

For Lori Senecal, the primary measure of success is the outcomes. She leverages the creativity and innovativeness of the team at CP+B to help her grow the business and succeed. Lori has learned the importance of investing in opportunities that allow employees to develop such as training and other educational opportunities. She believes in tapping employee ideas and feedback over always forcing her visions on them.

Lori is the former Global Chair and CEO of KBS+. During her time at KBS+, on the 3% Conference, she accorded her employees an opportunity to pursue a course in venture capital. Lori intended to awaken an entrepreneurial spirit amongst them for the greater good of the agency. Later, she held a competition at the company to crowd source ideas from the employees that could make operations efficient or improve general morale. The competition started as a means to encourage creativity and has since evolved into a platform that showcases events, product demonstrations, and events.

Advertising Week honored CP+B among the 2016 “Creative Innovators of the Year” and ranked it among the four 2016 Agency Executives to Watch. The company has also bagged significant accounts over the past year including Paypal, Hershey, and American Airlines. The company earned The Titanium Grand Prix award at the Cannes Lions Festival for the Domino’s campaign.



Coffee Properties Prolong Life

Coffee is an everyday hot beverage that boosts mind and energy levels with a great taste and aroma. It is believed to have great properties that are helpful in prolonging life, whether it is caffeinated or decaffeinated.

The studies were covered over 185,000 Americans and they proved the results were correct. It has also been carried out over other populations and it works whether you are black, white, Latino, Asian or African-American. The test lasted for 16 years and those who had drunk two or three cups of coffee had an 18% chance of evading death.
Additionally, a European study done over 520,000 people in 10 different countries reported that the coffee drinkers had a lower risk of death as compared to those who did not drink coffee. On the other hand, the study had no limits and it was impossible to determine the relationship that coffee had with the drinkers. In both studies, the smoker and non-smokers were separated as well as other influences that could hinder the results.
When looking for the best coffee with the most health benefits, you should try out Organo. Organo is a non-profit organization supporting the youth by offering great opportunities that allow them to be productive and also engage other members of their communities to ensure that the future generations stand a chance at positive change.
Organo products are mainly for coffee and tea. Some of the coffee products include:
• The gourmet black coffee is a robust blend of instant coffee with no added sugar or creamer with sufficient antioxidants.
• Café latte is a tasty blend of espresso coffee with creamer. It is made of quality Arabica and Robusta coffee beans.
• Café mocha is a decadent treat with a smoother taste that is blended with creamer and has a sweet flavor.
• Café supreme is more of an energy booster with a mild and flavorful kick since it contains ginseng, Ganoderma, and Eurycoma.

For more information follow Organo on Twitter.

OSI’s International Expansion and Why It Has been so successful

OSI Group has been a leader in the food processing industry since 1909 when it was established. Even though a lot has changed since then, one thing remains constant: the company’s commitment to providing its customers with nothing but the best. When the current CEO of the company, Sheldon Lavin, took over, he had one vision—to transform the company into a global enterprise—and he has been making small but steady steps towards that. OSI’s first operation outside the U.S. was the Beijing facility, which it opened in 1992. Since then, the company’s presence in China has grown vastly, and it now has several other operations in the country.

Over the years, OSI has been forming strategic partnerships with other companies in the food processing industry to expand its market reach. Over the past 12 months, it has opened 7 new facilities in various locations around the world. Its leaders put a lot of emphasis on growth and expansion, and are investing a lot in this. The company partners with clients to find out what they need so that they can provide them with exactly that.

Strategic Partnerships

OSI recently purchased a plant in Chicago that formerly belonged to Tyson Foods for $7.4 million. The plant makes various food items including bacon, meat balls, hotdogs, hamburgers, vegetable products and poultry products as well. The company also purchased Flagship Europe, which makes dips, sandwich fillings, dressings, sauce, pies and marinades. OSI formed a partnership with Daho Foods, a Dutch company that manufactures deli meats, snacks and convenience foods. Daho Foods has operations in Netherlands and Germany and serves 18 countries in Europe, so this new partnership will really increase OSI Industries’ market reach. Through all these new operations, OSI is able to meet the growing demand for its products in the U.S. and beyond.

OSI currently has 65 facilities in more than 15 countries including the U.K, Brazil, India, Poland, Canada, Spain and Germany among others. The headquarters of OSI are in Aurora, Illinois. However, it runs its operations as autonomous units with local managers and employees as they understand the locals better and are better placed to meet their unique needs.


The decentralized business structure that OSI uses has worked very well for it. That is one of the reasons why its international expansion has been so successful. There is no micromanaging by top executives who do not really understand the local markets. With the excellent leadership and winning business strategies used at the company, OSI is bound to grow tremendously in the coming years.

Learn More: www.fooddrink-magazine.com/sections/producers/1308-osi-group

Maximizing Social Security Benefits

David Giertz is one of the leading financial advisors in the country. He has over thirty years of experience in the financial service industry. He is an accomplished, visionary, and inspirational leader. He has a proven track record of growing revenues by billions in the companies he has worked with. He has also worked with many community organizations.

Mr. David L. Giertz is a fifty three year old who graduated with a Bachelor of Science Degree from the University of Millikin. Additionally, Dave is a certified business coach with WABC and an industry arbiter with FINRA. Between 2004 to 2009, David served as the Vice President-NF Sales at the Bank Channel. On April 3, 2013, Mr. Giertz joined Nationwide Life Insurance Company as Senior Vice President-Nationwide Financial Distribution and Sales.

Myths about SS

Misconceptions abound about the right time to begin reaping retirement benefits. As a result, many retirees receive less income or unexpected taxes. SS is taxed when beneficiaries take it before retirement and continue to work. The government deducts one dollar for benefit payments for every two dollars that one earns above the annual limit. Additionally, beneficiaries do not understand factors that are used in determining amount of Social Security or that they are permanent. However, waiting or delaying to enjoy these benefits increases them by eight percent of the full retirement amount. Therefore, waiting for just a few more years beyond thee age of sixty two allows retirees to earn as much as they want.

Planning for Retirement

One way of coming up with a solid plan for a peaceful retirement is by taking into consideration other income opportunities. Investment is an option, but it has to be well calculated. For instance, future retirees should time their investments well. Another way is to compliment a savings account with a brokerage one. Doing this gives one access to currencies, bonds, and stokes where they can be sold for profit. Also, brokerage accounts are flexible because they do not limit investment and withdrawal amounts. A health saving account is also useful, but only when used for conditional medical expenses.

Choosing The Right Bank For Your Needs

Are you looking for a good bank in the Dallas, Texas area? Want to find a bank that has a good reputation due to their excellent service? Perhaps you have heard a lot of good things about Nexbank and wonder if the bank will meet your needs.

Nexbank is one of the leading financial institutions in the country. Nexbank has been providing a vast range of financial services to businesses and individuals for many years and comes highly recommended in the industry. Anyone who is in need of expert advice regarding banking, money management or financial advisory, should consider Nexbank.

Choosing the right bank for your personal or business banking shouldn’t be a daunting task. If you’re trying to decide which bank or financial institution best fits your needs, you’ll want to find out which features or services are available to you. It can also be helpful if you’re considering switching your bank.

There are many banks and financial institutions to research before making a decision. Not all banks or financial institutions are created equal. Each bank offers many different services and features to customers and clients.

You will want to find a good bank that has been catering to customers, and providing outstanding services. You may want to read reviews or contact current customers to find out how satisfied they are with the services they receive from the bank or financial institution you have in mind.

Based in Dallas, Texas, Nexbank is well known for providing top notch advisory service and financial solutions to those who need expert assistance in investing or managing their money. The financial and banking professionals at Nexbank are highly knowledgeable and experienced, and they are fully committed to providing the best quality service possible.